Towards better DNA chip hybridization using chaotic advection

Towards better DNA chip hybridization using chaotic advection

Numerical modeling of DNA-chip hybridization with chaotic advection.

We present numerical simulations of DNA-chip hybridization, both in the "static" and "dynamical" cases. In the static case, transport of free targets is limited by molecular diffusion; in the dynamical case, an efficient mixing is achieved by chaotic advection, with a periodic protocol using pumps in a rectangular chamber. This protocol has been shown to achieve rapid and homogeneous mixing. We...

Chaotic Advection Enhanced Remediation

Mixing, Chaotic Advection, and Turbulence

The establishment of a paradigm for mixing of fluids can substantially affect the development of various branches of physical sciences and technology. Mixing is intimately connected with turbulence, Earth and natural sciences, and various branches of engineering. However, in spite of its universality, there have been surprisingly few attempts to construct a general framework for analysis. An ex...

Chaotic advection and targeted mixing.

The advection of passive tracers in an oscillating vortex chain is investigated. It is shown that by adding a suitable perturbation to the ideal flow, the induced chaotic advection exhibits two remarkable properties which do not hold in the case of a generic perturbation: Particles remain trapped within a specific domain bounded by two oscillating barriers (suppression of chaotic transport alon...